Gene Targeting in Antibiotics-Producing Actinomycetes
نویسندگان
چکیده
منابع مشابه
Multiple resistance to aminoglycoside antibiotics in actinomycetes.
Actinomycetes were characterized in terms of resistance to 11 different aminoglycoside antibiotics (AGs). Strains freshly isolated in AG containing media showed wide varieties of multiple AG resistance, while the majority of ISP (International Streptomyces Project) cultures and the actinomycete strains isolated in an AG free medium were susceptible to all or most of the AGs tested. Marked chara...
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L Glutaminase, a therapeutic enzyme obtained from marine Actinomycetes gains importance because of their adaptability to varied environmental factors. An experimental study was carried out to isolate the L glutaminase producing actinomycetes from the marine sediment of Thoothukudi. Marine sediment sample was collected from six different locations of the Thoothukudi coastal ecosystem, enriched w...
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Glycopeptides such as vancomycin are the drugs of last resort for the treatment of severe infections caused by antibiotic resistant gram-positive bacteria. As a model strain for analysing and manipulating glycopeptide biosynthesis we have chosen Amycolatopsis balhimycina which synthesizes the vancomycin-type glycopeptide balhimycin. The 66-kb gene cluster encoding the biosynthesis of balhimycin...
متن کاملAntibiotics Targeting Ribosomes
The charge separation across the membrane is performed by a set of cofactors termed the electron transfer chain (Figure 9). It consists of three pairs of chlorophylls and one pair of phylloquinones (Vitamin K1), positioned along the pseudo-C2 axis in two branches, followed by the 4Fe4S cluster FX that is located right on the pseudo-C2 axis and coordinated to both PsaA and PsaB.The electron is f...
متن کاملRules for the classification of antibiotic-producing actinomycetes.
One of the most important tasks in our present day science of antibiotics is the establishment of a completely rational taxonomy and nomenclature for antibiotic-producing organisms. A purposeful search for antibiotic substances is possible only with good knowledge of the species which produce them. A great many antibiotic-producing actinomycetes have been described recently. Investigators often...
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ژورنال
عنوان ژورنال: Nippon Nōgeikagaku Kaishi
سال: 1996
ISSN: 0002-1407,1883-6844
DOI: 10.1271/nogeikagaku1924.70.889